Plaintiffs in Proton-Pump Litigation Seek MDL in Louisiana

nexium-b-1The Judicial Panel on Multidistrict Litigation will decide at a hearing on Jan. 26 in Miami whether to create a new MDL 2757 in Louisiana to consolidate dozens of lawsuits nationwide filed against manufacturers of proton pump inhibitor (PPI) heartburn medicines.

15 actions are pending in 12 different United States District Courts. Plaintiffs’ counsel have over 5,000 Proton-Pump Inhibitor possible cases under investigation and expect to file nearly 100 new lawsuits in the coming weeks.

PPIs are a group of drugs intended to act as hydrogen potassium ATPase (“H+/K+ ATPase”) enzyme inhibitor to block the production of gastric acid. The plaintiffs were prescribed a PPI by a physician and were later diagnosed with kidney injuries including acute interstitial nephritis (AIN), chronic kidney disease (CKD), and renal failure, also known as end-stage renal disease (ESRD). The complaints charge negligence, design defect, failure to warn, fraudulent concealment, warranty claims, and loss of consortium.

The defendants include:

  • AstraZeneca Pharmaceuticals LP
  • AstraZeneca LP
  • AstraZeneca PLC
  • Pfizer, Inc.
  • Procter & Gamble Manufacturing Company
  • The Procter & Gamble Company
  • Takeda Pharmaceuticals USA, Inc.
  • Takeda Pharmaceuticals America, Inc.
  • Takeda Pharmaceuticals International, Inc.
  • Takeda Development Center Americas, Inc.
  • Takeda Pharmaceutical Company Limited

Initial symptoms can be non-specific, such as fatigue, nausea and weakness. However, failure to treat interstitial nephritis (AIN) can lead to kidney death, dialysis, a kidney transplant or death.

The plaintiffs recommended the MDL be created in the federal Middle District of Louisiana in Baton Rouge before Chief Judge Brian A. Jackson, Judge Shelly D. Dick, Judge John W. deGravelles or Senior Judge James Joseph Brady. Alternatively, they would accept venues including the District of New Jersey, Southern District of Illinois, the District of Kansas or the Western District of Louisiana.

The motion was filed by Paul J. Pennock of Weitz & Luxenberg in New York.



Larry Bodine

Attorney Larry Bodine is Editor of Mass Tort Nexus, and the Editor of The National Trial Lawyers. He is the former Editor in Chief of and the American Bar Association Journal. He is a cum laude graduate of both Seton Hall University Law School and Amherst College.

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